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DESCRIPTION:Séminaires / soutenance-0
X-WR-CALDESC:Séminaires / soutenance-0
X-WR-CALNAME:Séminaires/soutenances du LIPhy
X-PUBLISHED-TTL:PT15M
SUMMARY:Séminaires/soutenances du LIPhy
BEGIN:VTIMEZONE
TZID:Europe/Paris
LAST-MODIFIED:20251211T094730Z
TZURL:https://www.tzurl.org/zoneinfo-outlook/Europe/Paris
X-LIC-LOCATION:Europe/Paris
BEGIN:DAYLIGHT
TZNAME:CEST
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
DTSTART:19700329T020000
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DTSTART:19701025T030000
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BEGIN:VEVENT
UID:TU1905245867
DTSTAMP:20260702T135606Z
SUMMARY:Bubbles: how they make noise\, and how they can absorb it (Valentin
  Leroy (Laboratoire Matière et Systèmes Complexes\, Paris))
DESCRIPTION:Who: Valentin Leroy (Laboratoire Matière et Systèmes Complexe
 s\, Paris)\n\nA bubble makes a sound when it detaches. While the frequency
  of this sound is well understood\, there has been no consensus on what ca
 uses its amplitude. Although mechanisms based on shape oscillations\, init
 ial velocity\, neck collapse or Laplace pressure have been suggested\, the
 se have not been systematically verified through experimentation. Our expe
 riments\, with bubbles released from a nozzle or entrapped by the impact o
 f a drop\, show that the initial velocity scenario provides a reasonable p
 rediction of the sound amplitude\, over three orders of magnitude. We refi
 ned this scenario by describing how the bubble velocity is affected by gas
  exchange through the closing neck. This ``leaking bubble'' model predicts
  that the bubble begins to produce sound prior to detachment\, as observed
  experimentally. By feeding image analysis of the neck into the model\, we
  obtained excellent agreement between the experimental and the calculated 
 pressure signals.\n\nBubbles can also absorb sound. A thin flexible coatin
 g consisting of air cavities embedded in a rubber elastomer can achieve ac
 oustic absorption down to the kilo-hertz range. We demonstrate this by cha
 racterizing a standard commercial aquarium\, identifying its resonances\, 
 and designing an optimized bubble screen configuration that effectively re
 duces reflections in the 3–6 kHz range\, approaching the acoustic behavi
 or of an infinite open-water environment. Time-domain analysis confirms th
 at applying this coating significantly reduces tank reflections\, offering
  a practical method for improving the accuracy of underwater acoustic rese
 arch.\n\nContact: Benjamin Dollet\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260112T110000
DTEND;TZID=Europe/Paris:20260112T120000
CREATED:20250626T124942Z
LAST-MODIFIED:20251211T082313Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/1905245867
X-TEAMUP-WHO:Valentin Leroy (Laboratoire Matière et Systèmes Complexes\, 
 Paris)
END:VEVENT
BEGIN:VEVENT
UID:TU1965042103
DTSTAMP:20260702T135606Z
SUMMARY:Transport of beads\, bubbles and droplets in cylindrical microchann
 el : The role of inertia and deformations (Jean Cappello (Institut Lumièr
 e Matière\, Lyon))
DESCRIPTION:Who: Jean Cappello (Institut Lumière Matière\, Lyon)\n\nWhen 
 transported in microchannels at intermediate Reynolds number\, beads\, dro
 plets or bubbles show interesting dynamics such as lateral migration. For 
 rigid beads this migration is solely induced by inertial forces which lead
  to lateral motion of the particle until it reaches an equilibrium uncente
 red position in the microchannel. Transport of deformable objects as dropl
 ets or bubbles is even richer as the coupling between deformation and the 
 external flow results in another lateral migration force whose orientation
  depends on the viscosity ratio of the two phases. I will present a study 
 in which we investigate\, both experimentally and numerically\, the veloci
 ty and lateral position of beads\, droplets and bubbles transported in a c
 ylindrical pipe. By varying the object size\, the viscosity ratio\, the de
 nsity\, the Reynolds number and the capillary number\, we offer an exhaust
 ive parametric study exploring various dynamics from the non-deformable vi
 scous regime to the deformable inertial regime\, thus enabling us to highl
 ight the sole and combined roles of inertia and capillary effects on later
 al migration. Then\, focusing on the specific case of bubbles\, we further
  identify an intriguing regime at large deformations in which bubbles trav
 el faster than the maximum velocity of the carrier flow. We rationalize th
 is behavior in the limit of large bubbles and show that it originates from
  a reduction of the hydraulic resistance of the multiphase system. Finally
 \, we determine the key parameters governing the onset of this “superfas
 t” regime and demonstrate that it occurs only within a limited range of 
 capillary and Reynolds numbers.\n\nContact: Elise Lorenceau\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260126T110000
DTEND;TZID=Europe/Paris:20260126T120000
CREATED:20251006T082706Z
LAST-MODIFIED:20260113T144059Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/1965042103
X-TEAMUP-WHO:Jean Cappello (Institut Lumière Matière\, Lyon)
END:VEVENT
BEGIN:VEVENT
UID:TU2022483822
DTSTAMP:20260702T135606Z
SUMMARY:[Young Researchers Only] VSS presentations: UGA reporting unit || L
 IPHY référents égalité (Marine DELMOTTE || Romain MARI\, Samantha MICC
 IULLA)
DESCRIPTION:Who: Marine DELMOTTE || Romain MARI\, Samantha MICCIULLA\n\nThi
 s exceptional seminar aims to provide young researchers in the lab with ba
 sic and practical information about gender-based and sexual violence (GBSV
 ) and gender equality\, while helping to foster a respectful and supportiv
 e working environment for everyone. Representatives from UGA’s Vice Pres
 idency for Equality\, Parity\, and Non-Discrimination (DGD RH)\, together 
 with the laboratory’s Equality Representatives\, were invited to introdu
 ce themselves\, share their current projects\, and provide key information
  on GBSV and gender equality.\n\n**Presentation of UGA’s reporting unit*
 *\n\n*Marine DELMOTTE - (DGD RH)*\n\nThis presentation will introduce the 
 university’s reporting unit\, outlining its role\, procedures\, and avai
 lable support\, while also providing an overview of UGA’s initiatives\, 
 tools\, and resources aimed at promoting gender equality and preventing di
 scrimination across the university community.\n\n**Presentation of LIPHY's
  référents égalité**\n\n*Romain MARI\, Samantha MICCIULLA (PSM\, MODI)
 *\n\nThis presentation will introduce the laboratory’s Equality Officers
  and highlight their ongoing activities and new initiatives\, aimed at add
 ressing gender bias and discrimination within the laboratory.​\n\n
LOCATION:Conference Room (Liphy)
CATEGORIES:Séminaire des non-permanents
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260130T101500
DTEND;TZID=Europe/Paris:20260130T120000
CREATED:20260112T092105Z
LAST-MODIFIED:20260128T035948Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2022483822
X-TEAMUP-WHO:Marine DELMOTTE || Romain MARI\, Samantha MICCIULLA
X-TEAMUP-WHERE:Conference Room (Liphy)
END:VEVENT
BEGIN:VEVENT
UID:TU2009129871
DTSTAMP:20260702T135606Z
SUMMARY:Continuum des financements des projets de valorisation (Sara Matyas
  (CNRS Innovation))
DESCRIPTION:Who: Sara Matyas (CNRS Innovation)\n\nLes financements de valor
 isation sont nombreux\, chacun avec ses guichets\, ses règles et ses crit
 ères… Et si on éclaircissait ce sujet ensemble ? À partir d’exemple
 s concrets\, nous parcourrons les différents chemins possibles pour valor
 iser un projet de recherche\, depuis l’idée fondamentale jusqu’à sa 
 valorisation. Vous verrez que la start‑up n’est qu’une option parmi 
 d’autres. L'objectif : décoder clairement les informations essentielles
  à retenir pour chaque type de financement et comprendre la dynamique du 
 continuum (Pré‑maturation CNRS\, Pré‑maturation PUI\, Maturation SAT
 T\, programme RISE\, BTF Lab\, Incubation\, Transfert\, Licensing…).\n\n
 Contact: Bahram Houchmandzadeh\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260202T110000
DTEND;TZID=Europe/Paris:20260202T120000
CREATED:20251217T111942Z
LAST-MODIFIED:20260127T143103Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2009129871
X-TEAMUP-WHO:Sara Matyas (CNRS Innovation)
END:VEVENT
BEGIN:VEVENT
UID:TU2001007913
DTSTAMP:20260702T135606Z
SUMMARY:Understanding DNA replication dynamics in the archaea Haloferax vol
 canii (Roxane Lestini and Nicolas Olivier (Laboratoire d'Optique et Biosci
 ences\, Palaiseau))
DESCRIPTION:Who: Roxane Lestini and Nicolas Olivier (Laboratoire d'Optique 
 et Biosciences\, Palaiseau)\n\nArchaea provide a simplified yet highly inf
 ormative model for deciphering the complex regulatory networks governing D
 NA replication and origin firing. Among them\, Haloferax volcanii has a ci
 rcular chromosome with four active replication origins distributed across 
 a 3.5 Mb DNA molecule and exhibit some distinctive properties\, such as a 
 heterogeneous polyploidy\, carrying 10–18 copies of its genome.\n\nHow t
 hese highly polyploid organisms regulate the activation and timing of thei
 r multiple replication origins in coordination with cell growth and divisi
 on remains an open question. To address this question\, we developed a mul
 tiscale approach\, implementing the STORM technique in archaea for the fir
 st time\, Marker Frequency Analysis by sequencing (MFA-seq) to capture the
  global replication profile at the population level\, and fluorescence in 
 situ hybridization (FISH) to explore ploidy variation.\n\nOur findings rev
 eal\, with an unprecedented resolution of ~30 nm\, new insights into the s
 patial regulation of replication foci\, demonstrating their organization i
 nto clusters. We further investigated DNA replication dynamics under varyi
 ng growth conditions\, revealing a reduction in replication foci number th
 at correlates with decreased replication rates and DNA content. By contras
 t\, altering the replication initiation mode—by inactivating all four re
 plication origins—does not disrupt the overall replication dynamics.\n\n
 By integrating these techniques\, we aim to characterize the replication p
 rogram in H. volcanii and gain a deeper understanding of its regulation.\n
 \nContact: Delphine Débarre\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260216T110000
DTEND;TZID=Europe/Paris:20260216T120000
CREATED:20251203T193111Z
LAST-MODIFIED:20260109T092254Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2001007913
X-TEAMUP-WHO:Roxane Lestini and Nicolas Olivier (Laboratoire d'Optique et B
 iosciences\, Palaiseau)
END:VEVENT
BEGIN:VEVENT
UID:TU2045923369
DTSTAMP:20260702T135606Z
SUMMARY:HDR Pierre RECHO (Pierre RECHO)
DESCRIPTION:Who: Pierre RECHO\n\n**Mechanics of cells and living tissues**\
 n\nMy broad goal is to develop and study mechanical models to understand h
 ow cells control their shape\, volume and motility to perform collective t
 asks and self-organize into tissues. These functions play a crucial role i
 n many biological phenomena including wound healing\, inflammation\, remod
 eling of connecting tissues\, rebuilding of damaged structures and formati
 on of metastases in cancer. The aim of my research is to embed the cell’
 s active functions within the framework of passive rheology while respecti
 ng the overarching principles of thermodynamics to formulate constitutive 
 laws for cellular material. This in turn opens new boundary-value problems
  in continuum mechanics\n\nJury composition:\n\n•Bertrand Fourcade (LiPh
 y) Président\n\n•Alice Nicolas(LTM) Rapportrice\n\n•Pasquale Ciarlett
 a (MOX) Rapporteur\n\n•Hélene Delanoe-Ayari (ILM) Rapportrice\n\n•Ang
 élique Stéphanou(TIMC) Examinatrice\n\n•Davide Ambrosi (DISMA) Examina
 teur\n\n•Matthieu Caruel (MSME) Examinateur\n\n
CATEGORIES:Soutenances
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260226T140000
DTEND;TZID=Europe/Paris:20260226T150000
CREATED:20260219T105925Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2045923369
X-TEAMUP-WHO:Pierre RECHO
END:VEVENT
BEGIN:VEVENT
UID:TU2037005883
DTSTAMP:20260702T135606Z
SUMMARY:[Young Researchers Only]: Modeling the emission spectra of polycycl
 ic aromatic hydrocarbons by recurrent fluorescence || On the physico-chemi
 stry of polyvinyl butyral: Elegance behind complexity. (Borja DAMIEN - (Ph
 D\, PSM) || Arauz Moreno CARLOS - (Post-Doc\, OPTIMA))
DESCRIPTION:Who: Borja DAMIEN - (PhD\, PSM) || Arauz Moreno CARLOS - (Post-
 Doc\, OPTIMA)\n\n**Modeling the emission spectra of polycyclic aromatic hy
 drocarbons by recurrent fluorescence**\n\n *Borja DAMIEN - (PhD\, PSM)*\n\
 nThe presence of polycyclic aromatic hydrocarbons (PAHs) in interstellar m
 edium (ISM) is supported by the observation of aromatic infrared bands in 
 emission spectra\, and the detection of several individual PAH species. Th
 e importance of recurrent fluorescence (RF) in their relaxation process co
 uld significantly increase their stability in such highly ionized environm
 ents. I present a statistical model of relaxation by RF\, including Duschi
 nsky rotation and Herzberg-Teller effects as well as a full account of vib
 rational progressions\, and its application to naphthalene\, anthracene\, 
 and pyrene cations. For these highly symmetric molecules\, the low energy 
 symmetry-forbidden electronic transitions are predicted to contribute more
  to RF than the traditionally considered\, higher energy\, non-forbidden t
 ransitions. This unexpected contribution could increase the cooling effici
 ency of PAHs and their stability under the highly ionized conditions of th
 e ISM.\n\n---\n\n**On the physico-chemistry of polyvinyl butyral: Elegance
  behind complexity.**\n\n*Arauz Moreno CARLOS - (Post-Doc\, OPTIMA)*\n\nPo
 lyvinyl butyral (PVB) is an amorphous polymer typically used in laminated 
 safety glass or solar panels. In both cases\, a thin PVB sheet serves as a
 n adhesive between two layers of glass. While highly relevant industrially
 \, PVB polymers remain poorly understood at a fundamental level\, despite 
 their interesting chemistry and equally appealing physical properties. In 
 this talk\, I will discuss recent advances in the understanding of PVB pol
 ymers which link chemistry to macroscopic properties\, such as rheology\, 
 water transport and clustering\, as well as dynamic bubbling behavior – 
 all key properties that impact the performance of glass assemblies with PV
 B polymers.\n\n
LOCATION:Conference Room
CATEGORIES:Séminaire des non-permanents
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260227T110000
DTEND;TZID=Europe/Paris:20260227T120000
CREATED:20260204T123726Z
LAST-MODIFIED:20260225T145556Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2037005883
X-TEAMUP-WHO:Borja DAMIEN - (PhD\, PSM) || Arauz Moreno CARLOS - (Post-Doc\
 , OPTIMA)
X-TEAMUP-WHERE:Conference Room
ATTACH:https://files.teamup.com/16073145/attachment/01KJAKGSSAE803ZR36NEDCA
 FG6/tot_abstract.png?hash=7cf375cda2b8bd839034f279879d7adc843bb2655d168039
 eba6b84ed4eecef0
ATTACH:https://files.teamup.com/16073145/attachment/01KJAKGSSXY9GYM7MTS80ET
 YC8/Damien_pic.jpg?hash=2f886c843173e520d0c3ddc5585a0ccf791d2b741368ff0d0c
 2a8f0a3ab76264
ATTACH:https://files.teamup.com/16073145/attachment/01KJAKGSV7QSKJ8AW4SSJ5E
 FV0/CArauz.jpg?hash=fde0ff68bc992909e64c23eaae3ee617073aa23a3368b2c89d727a
 bf19ee2f6f
END:VEVENT
BEGIN:VEVENT
UID:TU2018905838
DTSTAMP:20260702T135606Z
SUMMARY:Ultrafast imaging of membrane potential and Ca2+ transients in brai
 n slices from individual neurons and networks (Marco Canepari)
DESCRIPTION:Who: Marco Canepari\n\nThe brain slice is a living tissue\, kep
 t under physiological conditions for up to 6 hours\, where neurons and loc
 al circuitries are preserved as *in vivo*. In this preparation\, it possib
 le to inject Ca2+ indicators and voltage sensitive dyes (VSDs) into indivi
 dual neurons and perform ultrafast (5-40 kHz) imaging to record membrane p
 otential (Vm) and Ca2+ transients\, associated with stimulated activity\, 
 in specific sub-cellular compartments such as axons\, dendrites and synapt
 ic spines. Ca2+ indicators and VSDs can be also loaded in the whole slice\
 , losing the ability to resolve single cells but gaining the possibility t
 o monitor network activity. Vm imaging allows recording action potentials 
 and synaptic potentials while Ca2+ influx\, triggered by Vm signals\, can 
 be imaged and correlated with electrical activity. In fundamental neurosci
 ence\, this approach permits the unravelling of complex ion channels syner
 gies as well as the interactions with other molecules underlying neuronal 
 function. In preclinical research\, the same strategy allows untangling dy
 sfunctions caused by genetic mutations in animal models of human disease. 
 Finally\, combining Vm and Ca2+ imaging is a powerful tool to investigate 
 the effect of drugs on neuronal excitability\, synaptic transmission and g
 lobal network activity. In the project *SynBin*\, we will use our high-res
 olution imaging approaches to explore diversity of synaptic spines in the 
 same cerebellar Purkinje neuron. This project challenges classical learnin
 g theories assuming that synapses of a given type are identical except for
  variations of receptor numbers resulting from plasticity\, whereas eviden
 ce suggests that synapses have specific molecular identities\, implying no
 vel hypotheses regarding the mechanisms of synaptic computations\, plastic
 ity and their role in learning and memory. In the project *Chlorzowill*\, 
 we will study an animal model of the Williams-Beuren syndrome\, a rare gen
 etic disease caused by deletion of several contiguous genes resulting in n
 eurological and cardiovascular alterations. Grounded on the evidence that 
 the disease is associated with the down-regulation of BK K+ channels\, we 
 will explore neuronal excitability on the animal model and the potential t
 herapeutic effect of chlorzoxazone targeting this type of channels. Finall
 y\, whole-slice combined Vm and Ca2+ imaging can be exploited to rapidly a
 nd efficiently assess the acute effects of drugs in the long industrial le
 ad-selection process that precedes clinical trials. A technology transfer 
 project is ongoing on this topic.\n\n
CATEGORIES:Séminaires internes
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260305T110000
DTEND;TZID=Europe/Paris:20260305T120000
CREATED:20260106T133928Z
LAST-MODIFIED:20260204T184403Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2018905838
X-TEAMUP-WHO:Marco Canepari
END:VEVENT
BEGIN:VEVENT
UID:TU2053912100
DTSTAMP:20260702T135606Z
SUMMARY:[Young Researchers Only]: Mitochondrial mechano-remodeling​. || S
 ubstrate cleaning by polymer coat\, crack & peel​. (Eloina CORRADI - (Po
 st-Doc\, MicroTiss) || Mona MOUKRATI - (PhD\, MODI))
DESCRIPTION:Who: Eloina CORRADI - (Post-Doc\, MicroTiss) || Mona MOUKRATI -
  (PhD\, MODI)\n\n**Mitochondrial mechano-remodeling​.**\n\n *Eloina CORR
 ADI - (Post-Doc\, MicroTiss)*\n\nMitochondria are double-membrane organell
 es that sustain the bioenergetic metabolism of cells by producing ATP at t
 he level of the cristae\, convoluted folds of the inner membrane. ATP prod
 uction efficiency and mitochondrial morphology\, including cristae archite
 cture\, are tightly linked. Consequently\, by being coupled to mitochondri
 al function\, the reshaping of mitochondria across spatial scales regulate
 s the cellular bioenergetic and metabolic states. Mechanical stimuli have 
 recently been shown to modulate cellular metabolism\, thus impacting physi
 ological (e.g. cell migration\, proliferation\, death) and pathological (e
 .g. cancer progression) processes. ​\n\nHere\, using a unique biomechani
 cal tool to stretch cells\, we show that mechanical stimulation drasticall
 y re-shape mitochondria across spatial scale\, deforming and modulating bo
 th external and internal architecture\, impacting cell metabolism. ​\n\n
 ---\n\n**Substrate cleaning by polymer coat\, crack &amp\; peel​.**\n\n*
 Mona MOUKRATI- (PhD\, MODI)*\n\nThe continuous miniaturization of microele
 ctronic devices imposes increasingly stringent requirements on surface cle
 anliness\, as nanoparticles above 10 nm critically threaten device perform
 ance. Conventional cleaning methods often damage delicate nanostructures o
 r lack sufficient nanoscale efficiency.​\n\nThis work investigates polym
 er-film-based cleaning via controlled delamination of polymethyl methacryl
 ate (PMMA)\, triggered by crack formation when the coated wafer is immerse
 d in ethanol. The influence of experimental parameters on crack morphology
  and propagation is systematically examined to better understand the under
 lying cracking mechanism. Applied to ceria-contaminated silicon wafers\, t
 his crack-induced delamination process achieves over 80% particle removal.
 ​\n\n​\n\n
LOCATION:Conference Room
CATEGORIES:Séminaire des non-permanents
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260313T110000
DTEND;TZID=Europe/Paris:20260313T120000
CREATED:20260304T073617Z
LAST-MODIFIED:20260310T094107Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2053912100
X-TEAMUP-WHO:Eloina CORRADI - (Post-Doc\, MicroTiss) || Mona MOUKRATI - (Ph
 D\, MODI)
X-TEAMUP-WHERE:Conference Room
ATTACH:https://files.teamup.com/16073145/attachment/01KKBHXB3FE4FTM6GHFK447
 D5S/MOUKRATI%20Mona%20B.jpg?hash=f7d0a6d453e86a72125f4cccf99f724aa2824b18b
 5bce1011d71cb71583990db
ATTACH:https://files.teamup.com/16073145/attachment/01KKBHXB46QF30RDK5EMA53
 A62/fig_abstract.png?hash=ab7a17127b74bc145f646aaaf8a99d845359d800878d9284
 789e7e65fb72c3fe
ATTACH:https://files.teamup.com/16073145/attachment/01KKBHXB4S2DSN197EC0DTP
 6PV/Eloina_portrait.jpeg?hash=30c20ba18c5e957b8de3d710d11429bfd83f6fa87355
 b241e7d66e7491b43098
END:VEVENT
BEGIN:VEVENT
UID:TU1947824725
DTSTAMP:20260702T135606Z
SUMMARY:A circadian clock in Bacillus subtilis (Martha Merrow (LMU Munich\,
  Germany))
DESCRIPTION:Who: Martha Merrow (LMU Munich\, Germany)\n\nThe circadian cloc
 k is a molecular machine that is present in each one of our cells\, direct
 ing diverse processes in a cell(developmentally)-specific manner. The natu
 ral state of the clock is ‘entrainment’\, namely through synchronizati
 on with zeitgeber signals (such as the light/dark cycle) in the environmen
 t. Once moved to constant conditions\, a free running rhythm of approximat
 ely 24h can be observed\, demonstrating the endogenous nature of the clock
 . One can understand how the clock relates to our lives by noting the timi
 ng of the sleep wake cycle: this is determined by the interaction of the b
 iological (circadian) oscillator and the external zeitgeber cycle. Disrupt
 ing the clock in humans and mice leads to increased cancers\, metabolic di
 sease and decreased cognitive performance\, likely through misexpression o
 f key regulators. The circadian clock is an essential aspect of biology an
 d its function can be regarded as a biophysical phenomenon.\n\nCircadian c
 locks have been described in all kingdoms of life except for the Eubacteri
 a – until very recently. I will discuss the circadian clock in the model
  prokaryote\, Bacillus subtilis. We observe rhythms in gene expression\, i
 n colony morphology on agar\, and in metabolism and in planktonic cultures
 . The circadian transcriptome shows pervasive regulation of gene expressio
 n by the biological clock\, even more extensively than sigma factors. The 
 clock is thus a major regulatory phenomenon in this bacterium. Our work be
 gs the questions ‘what is the same as clocks in higher organisms?’ and
  ‘what is different?’.\n\nContact: Irina Mihalcescu\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260316T110000
DTEND;TZID=Europe/Paris:20260316T120000
CREATED:20250908T130627Z
LAST-MODIFIED:20260227T075749Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/1947824725
X-TEAMUP-WHO:Martha Merrow (LMU Munich\, Germany)
END:VEVENT
BEGIN:VEVENT
UID:TU1984934570
DTSTAMP:20260702T135606Z
SUMMARY:Retours d'expérience de l'équipe BIOP sur le cahier de laboratoir
 e électronique eLabFTW (Catherine Bouchenot)
DESCRIPTION:Who: Catherine Bouchenot\n\nDepuis juin 2022\, le CNRS préconi
 se l'utilisation de cahier de laboratoire électronique (CLE) et propose 
 à cet effet une offre de service basée sur l'outil **elabFTW**.\n\nCe ch
 oix fait suite à un groupe de travail démarré en 2020 pour identifier d
 es solutions électroniques adaptées aux pratiques de la recherche en pre
 nant en compte la diversité des activités du CNRS tout en assurant la m
 émoire\, la traçabilité\, la sécurité\, la confidentialité et la pé
 rennité des résultats de recherche et tout en respectant les exigences l
 iées à la Science Ouverte et à la protection du patrimoine scientifique
  et technique de l’établissement.\n\n Sur le campus grenoblois\, GRICAD
  propose depuis 2020 une instance de elabFTW parmi la liste des outils mut
 ualisés à disposition des laboratoires du campus.\n\nAu sein du Liphy\, 
 l'équipe BIOP s'est portée volontaire en 2023 en tant qu'équipe pilote 
 pour l'utilisation de eLabFTW.\n\nCette présentation propose un retour d'
 expérience de cette équipe pilote sur l'utilisation de cet outil de CLE\
 ; ce sera aussi l'occasion de présenter elabFTW et ses fonctionnalités.\
 n\n
CATEGORIES:Séminaires internes
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260319T110000
DTEND;TZID=Europe/Paris:20260319T120000
CREATED:20251106T154836Z
LAST-MODIFIED:20260204T184653Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/1984934570
X-TEAMUP-WHO:Catherine Bouchenot
END:VEVENT
BEGIN:VEVENT
UID:TU2024869317
DTSTAMP:20260702T135606Z
SUMMARY:Uncovering the forces driving the fate and shape of the extraembryo
 nic amnion during human gastrulation (Chloé Roffay (IMP Vienna\, Austria)
 )
DESCRIPTION:Who: Chloé Roffay (IMP Vienna\, Austria)\n\nExtraembryonic tis
 sues provide key molecular signals and mechanical support to the growing e
 mbryo. For instance\, the extraembryonic amnion\, which forms a fluid-fill
 ed sac surrounding the embryo\, was recently shown to trigger germ layer s
 pecification during gastrulation\, by secreting BMP ligands. Despite the k
 ey roles of extraembryonic tissues in embryo development\, little is still
  known regarding their molecular and biophysical programs\, particularly i
 n human. Using a 2D stem cell-based model of human gastrulation\, termed g
 astruloid discs\, we found that amnion cells undergo a sharp columnar-to-s
 quamous transition concomitantly with fate specification. Via biophysical 
 modelling\, direct force measurements\, pharmacological and genetic pertur
 bations\, we showed that this morphogenetic transition is amnion-intrinsic
  and it is driven by active wetting\, i.e. a transition from tensile to ad
 hesion-dominated cellular states. Molecularly\, active wetting is implemen
 ted via a rewiring of cytoskeleton composition\, from actomyosin to kerati
 n-based cytoskeletal networks\, akin to a bistable toggle-switch in gene r
 egulatory networks. Strikingly\, blocking shape changes at the colony edge
  results both in defective cellular states in the amnion and impaired gast
 ruloid disc morphogenesis within the embryonic compartment. Together\, our
  findings establish that a cytoskeletal toggle switch couples fate specifi
 cation to tissue architecture in the human amnion and suggest an unexpecte
 dly active mechanical role for extraembryonic tissues in shaping the embry
 o proper.\n\nContact: Thomas Boudou\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260323T110000
DTEND;TZID=Europe/Paris:20260323T120000
CREATED:20260115T135555Z
LAST-MODIFIED:20260312T135227Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2024869317
X-TEAMUP-WHO:Chloé Roffay (IMP Vienna\, Austria)
END:VEVENT
BEGIN:VEVENT
UID:TU2059068127
DTSTAMP:20260702T135606Z
SUMMARY:Role of defects in morphogenesis and wrinkling (Arthur Hernandez (L
 eiden University\, the Netherlands))
DESCRIPTION:Who: Arthur Hernandez (Leiden University\, the Netherlands)\n\n
 The emergence of a body axis is a fundamental step in the development of m
 ulticellular organisms. For example\, in simple systems such as Hydra\, gr
 owing evidence suggests that mechanical forces generated by collective cel
 lular activity play a central role in this process. In this seminar\, I wi
 ll propose a physical mechanism for axis formation based on the coupling b
 etween active stresses and tissue elasticity. The interplay between elasti
 c deformations induced by activity-generated stresses\, nematicity\, and s
 pherical topology results in a global condensation of forces and defects w
 hich defines either a bipolar or polar head-foot axis. Compact parametriza
 tions of the active force and flux distributions enable analytical predict
 ions and direct comparison with experimental data on tissue stretching of 
 Hydra. Within this framework\, one may calculate relevant observables incl
 uding areal strain\, lateral pressure\, and normal displacements during mu
 scular contraction\, as well as the detailed structure of topological defe
 ct complexes in head and foot regions. Together\, these results identify a
  mechanical route by which active tissues can spontaneously break symmetry
  at the organismal scale\, suggesting a general physical principle underly
 ing body-axis specification during morphogenesis. Time permitting\, I will
  also discuss extensions of this framework towards wrinkling of active nem
 atic sheets where the feedback between nematic defects and spontaneous cur
 vature can engender a diverse morphology of wrinkle patterning.\n\nContact
 : Alexander Erlich\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260402T110000
DTEND;TZID=Europe/Paris:20260402T120000
CREATED:20260312T113337Z
LAST-MODIFIED:20260330T075034Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2059068127
X-TEAMUP-WHO:Arthur Hernandez (Leiden University\, the Netherlands)
END:VEVENT
BEGIN:VEVENT
UID:TU2036186932
DTSTAMP:20260702T135606Z
SUMMARY:Mechanical signaling through motility before settlement (Manon Vale
 t (MC2))
DESCRIPTION:Who: Manon Valet (MC2)\n\nTo complete their life cycles\, many 
 marine invertebrate species undergo metamorphosis\, a key transition from 
 their larval\, planktonic stage to the adult benthic form. When\, where\, 
 and how larvae choose to initiate the process remain debated. To address t
 his matter\, I propose to study the coupling between ciliary and neuronal 
 activity in sea urchin larvae close to a solid/liquid interface mimicking 
 the seabed.\n\nDuring this talk “without results”\, I will motivate th
 e choice of this non-conventional model system to develop an interdiscipli
 nary project linking developmental biology\, signalization\, and biophysic
 s. I will present the main ideas structuring the project and how I would l
 ike to conduct it at LIPhy.\n\n
CATEGORIES:Séminaires internes
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260409T110000
DTEND;TZID=Europe/Paris:20260409T120000
CREATED:20260203T085229Z
LAST-MODIFIED:20260407T110845Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2036186932
X-TEAMUP-WHO:Manon Valet (MC2)
END:VEVENT
BEGIN:VEVENT
UID:TU2058428218
DTSTAMP:20260702T135606Z
SUMMARY:Granular heap on an elastic membrane : statics and dynamics (Sophie
  Monnery (Institut Jean le Rond d’Alembert\, Paris))
DESCRIPTION:Who: Sophie Monnery (Institut Jean le Rond d’Alembert\, Paris
 )\n\nWhen granular material is poured onto an elastic membrane\, it forms 
 a heap whose weight deforms the membrane. The membrane’s deformation\, i
 n turn\, constrains the heap’s geometry\, causing its aspect ratio to de
 viate from the classic triangular profile. This coupling is governed by a 
 dimensionless number that captures the balance between the membrane’s el
 asticity and the granular weight in this simplified elasto-granular system
 . We introduce an incremental model to predict the heap’s temporal evolu
 tion\, accounting for its spreading and growth as mass is added.\n\nThen\,
  upon introducing energy into the system by vibrating the elastic support\
 , grains rearrangements reshape the heap’s apex\, giving rise to new con
 figurations\, including a “volcano-like” profile that is more compact.
  At even higher vibrational amplitudes\, grains begin to detach from the b
 ulk and to bounce on the membrane\, with spiraling trajectories.\n\nContac
 t: Philippe Marmottant\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260413T110000
DTEND;TZID=Europe/Paris:20260413T120000
CREATED:20260311T133011Z
LAST-MODIFIED:20260313T133458Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2058428218
X-TEAMUP-WHO:Sophie Monnery (Institut Jean le Rond d’Alembert\, Paris)
END:VEVENT
BEGIN:VEVENT
UID:TU2069808903
DTSTAMP:20260702T135606Z
SUMMARY:[Young Researchers Only]: Tuning the echanics of fibrous tissues wi
 th​ optogenetics​. || Acoustics of single-reed instruments and the mec
 hanical characterization of reeds​. (Thibault BRAM DIT SAINT AMAND - (Ph
 D\, Microtiss) || Camille URBAN- (PhD\, MOVE)​)
DESCRIPTION:Who: Thibault BRAM DIT SAINT AMAND - (PhD\, Microtiss) || Camil
 le URBAN- (PhD\, MOVE)​\n\n**Tuning the echanics of fibrous tissues with
 ​ optogenetics​.**\n\n*Thibault BRAM DIT SAINT AMAND - (PhD\, Microtis
 s)*\n\nIn connective tissues\, mechanical signals play a key role in the r
 egulation of biological processes. Fibroblasts\, a type of contracting cel
 ls\, can induce such signals\, deforming and remodeling over long distance
 s the extracellular matrix (ECM) allowing large-scale reorganization. ​\
 n\nIn this project\, we investigate the interactions between tissue contra
 ctility and its ECM to understand physiological mechanisms such as wound h
 ealing\, but also pathological mechanisms such as fibrosis. ​\n\nOur app
 roach involves the use of optogenetics\, a technique allowing dynamic modu
 lation of tissue forces with great spatiotemporal resolution. With light s
 timulation\, we managed to train fibrous tissues during their self-assembl
 y and tune their mechanics.​\n\n---\n\n**Acoustics of single-reed instru
 ments and the mechanical characterization of reeds​.**\n\n*Camille URBAN
 - (PhD\, MOVE)​*\n\nThe reed is a thin piece of carved cane essential to
  sound production in single-reed instruments\, such as the clarinet or the
  saxophone. It plays a crucial role in both sound quality and musician's p
 laying comfort. However\, even when reeds are sold as 'identical' by manuf
 acturers\, musicians often find significant differences between them. ​\
 n\nThis work aims to understand this phenomenon by identifying physical pa
 rameters that define and explain reed quality. In this presentation\, I wi
 ll introduce you to the acoustics of the clarinet and share my work from a
  previous internship focused on the mechanical characterization of reeds.
 ​​\n\n
LOCATION:Conference Room
CATEGORIES:Séminaire des non-permanents
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260424T110000
DTEND;TZID=Europe/Paris:20260424T120000
CREATED:20260330T090459Z
LAST-MODIFIED:20260421T124229Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2069808903
X-TEAMUP-WHO:Thibault BRAM DIT SAINT AMAND - (PhD\, Microtiss) || Camille U
 RBAN- (PhD\, MOVE)​
X-TEAMUP-WHERE:Conference Room
ATTACH:https://files.teamup.com/16073145/attachment/01KPR0MP83EAWX12D9JPKMG
 74Q/Camille_portrait.jpg?hash=c0a6befbb8e953cc4752a462223086ed70a1e53459a6
 7a956b640d922816c48e
ATTACH:https://files.teamup.com/16073145/attachment/01KPR0MP8X44Q3T9GFQR94P
 C75/Thibault_portrait.jpg?hash=6906dfb5469ea2d2c41c95af77f1961cc603c6362e9
 1e131113b0384aab3464e
ATTACH:https://files.teamup.com/16073145/attachment/01KPR0WXAQ7YMB13WSMB6XZ
 0WZ/fig_abstract.png?hash=c0be21f09e32b6f81371d32647959ff95a4f835d7fe55e66
 608fb368cff38285
END:VEVENT
BEGIN:VEVENT
UID:TU2038569180
DTSTAMP:20260702T135606Z
SUMMARY:Deciphering the origin of saddle-shape geometry in the microstructu
 re of echinoderms skeleton. (Giulio Facchini (Laboratoire Matière et Syst
 èmes Complexes\, Paris))
DESCRIPTION:Who: Giulio Facchini (Laboratoire Matière et Systèmes Complex
 es\, Paris)\n\nThe microstructure of echinoderms skeleton\, like sea stars
  and sea urchins\, is an impressive example of self-organization and compl
 exity. This structure called stereom is a porous meshwork\, made of calcit
 e\, whose surface is saddle-shaped\, and remind of minimal surfaces. Minim
 al surfaces have intrigued scientists for centuries\, as they can spontane
 ously emerge from minimizing interfacial energy like surface tension. Seve
 ral studies have addressed the morphogenesis of the stereom\, in sea urchi
 ns and other echinoderms\, showing that it forms via the addition of tiny 
 mineral bids at the tip of small skeletal elements that successively branc
 h and bridge to form a complex network. Yet\, a global\, mechanistic\, com
 prehension of how biomineralizing cells control preferential deposition is
  still lacking.\n\nDuring the seminar I will present a recent work1 on the
  morphogenesis of the particular stereom geometry observed in the sea star
  P. nodosus. Here\, the stereom can take the form of a diamond Triply Peri
 odic Minimal Surface (TPMS) which confer it specific mechanical properties
 . Using different marking protocols\, we provide the first experimental in
 sight in the formation of the diamond TPMS stereom\, and show that the for
 mation of such a highly ordered structure relies on a precise and timely c
 oordination of the branching and bridging episodes. Moreover\, we provide 
 experimental evidences of an organic precursor made of F – actin fibers 
 exhibiting saddle-shape geometry. We hypothesise that such a fibers templa
 te may self-organise under mechanical tension\, thus explaining the peculi
 ar curvature signature of the final structure. Finally\, I will present so
 me ongoing experimental work performed on sea urchins\, showing that the s
 ame morphogenetic mechanism could be shared across very different species.
 \n\nContact: Emmanuel Siéfert\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260504T110000
DTEND;TZID=Europe/Paris:20260504T120000
CREATED:20260206T183924Z
LAST-MODIFIED:20260422T123030Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2038569180
X-TEAMUP-WHO:Giulio Facchini (Laboratoire Matière et Systèmes Complexes\,
  Paris)
END:VEVENT
BEGIN:VEVENT
UID:TU2045212259
DTSTAMP:20260702T135606Z
SUMMARY:Géraldine Bozec - TBD
CATEGORIES:Séminaires internes
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260507T110000
DTEND;TZID=Europe/Paris:20260507T120000
CREATED:20260218T095557Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2045212259
END:VEVENT
BEGIN:VEVENT
UID:TU2048222636
DTSTAMP:20260702T135606Z
SUMMARY:From active particles to flexible\, deformable\, and motile superst
 ructures : a new type of soft robot of robots (Hamid Kellay (Laboratoire O
 ndes et Matière d'Aquitaine\, Bordeaux))
DESCRIPTION:Who: Hamid Kellay (Laboratoire Ondes et Matière d'Aquitaine\, 
 Bordeaux)\n\nWe study assemblies of rodlike robots made motile through sel
 f-vibration. When confined by circular scaffolds\, dilute assemblies of th
 ese rods act as a 2D gas of particles. Above a critical surface fraction\,
  some of the bots line up in one or more tight clusters along the corral b
 oundary while\, in the bulk\, gas-like behavior is retained. We find that 
 the unified pushing of the clustered bots on the boundary can drive collec
 tive motion: by selecting corrals that are deformable but free to move\, w
 e take advantage of surface cluster formation to force the robots to work 
 together. The deformability of the arena allows the assembly to go through
  narrow slits or to circumvent obstacles. Simple tasks such as pulling a l
 oad\, moving through an obstacle course\, or cleaning up an arena are demo
 nstrated. Rudimentary control of these superstructures (robots+scaffold) u
 sing light is also proposed.\n\nContact: Jean-Louis Barrat\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260511T110000
DTEND;TZID=Europe/Paris:20260511T120000
CREATED:20260223T144422Z
LAST-MODIFIED:20260412T063901Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2048222636
X-TEAMUP-WHO:Hamid Kellay (Laboratoire Ondes et Matière d'Aquitaine\, Bord
 eaux)
END:VEVENT
BEGIN:VEVENT
UID:TU2091608192
DTSTAMP:20260702T135606Z
SUMMARY:[Young Researchers Only]: The Power of Chickpeas: Understanding the
  Physics Behind Swelling Seeds. || Towards fully programmable inflatable p
 anels​​. (Alexia BEALE  - (Post-Doc\, MOVE) || Ofir MIRKIN- (PhD\, MOV
 E)​)
DESCRIPTION:Who: Alexia BEALE  - (Post-Doc\, MOVE) || Ofir MIRKIN- (PhD\, M
 OVE)​\n\n**The Power of Chickpeas: Understanding the Physics Behind Swel
 ling Seeds​.**\n\n*Alexia BEALE- (Post-Doc\, MOVE)*\n\nWhen preparing a 
 meal using chickpeas\, the chickpea seeds are typically soaked overnight i
 n water. Have you noticed that these chickpea seeds can swell up to ×2 th
 eir original volume? If a chickpea seed is rehydrated in a confined space\
 , it can exert a force of ~6 N on the boundary of its container. In my res
 earch\, I explore the physical properties and swelling dynamics of seeds\,
  using chickpeas as a model system. When placed underwater\, osmotic flow 
 leads to water uptake in the seed\, whilst diffusion plays a role in water
  transport within the seed. This talk will cover the swelling dynamics of 
 individual seeds\, an exploration of their structural composition during s
 welling and will answer the question of why some chickpeas wrinkle during 
 this process. ​\n\n---\n\n**Towards fully programmable inflatable panels
 ​​​.**\n\n*Ofir MIRKIN- (PhD\, MOVE)​*\n\nSelf-deployable material
 s are expected to have wide application potential\, e.g.\, in robotics\, m
 edicine\, and architecture. So far\, all responsive materials have limited
  deformation possibilities\, and researchers lack control over the six loc
 al degrees of freedom (three for the metric and three for the curvature). 
 Here\, we introduce a strategy to address this limitation. ​\n\nWe inves
 tigate how variations in mesoscale properties influence the deformation of
  inflatable elastic materials. Our structures feature a triangular network
  of interconnected cylindrical cavities\, and we study how their density\,
  eccentricity\, and orientation control the in-plane deformation. Using th
 ese results\, we solve an inverse problem of approximating target shapes. 
 ​\n\n
LOCATION:Conference Room
CATEGORIES:Séminaire des non-permanents
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260522T110000
DTEND;TZID=Europe/Paris:20260522T120000
CREATED:20260506T131611Z
LAST-MODIFIED:20260518T130703Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2091608192
X-TEAMUP-WHO:Alexia BEALE  - (Post-Doc\, MOVE) || Ofir MIRKIN- (PhD\, MOVE)
 ​
X-TEAMUP-WHERE:Conference Room
ATTACH:https://files.teamup.com/16073145/attachment/01KRXJYQFAPM0MR1YYFC1MS
 A80/Alexia_portrait.jpeg?hash=ca0a6ba03043546a73d7d09ddc367f0c3875c17298c5
 391c8b15a9d305be0b4c
ATTACH:https://files.teamup.com/16073145/attachment/01KRXK4XPBGGC2KS66YEAJ5
 1RB/abstract_fig.png?hash=036b32f213c46c685e3ff9e5032708277a70aed14bd62c66
 eea449c25dd76e26
END:VEVENT
BEGIN:VEVENT
UID:TU2070547609
DTSTAMP:20260702T135606Z
SUMMARY:HDR: Phage Display and microbial systems: the development of biorec
 eptors and their applications in biotechnology (Natale Scaramozzino)
DESCRIPTION:Who: Natale Scaramozzino\n\nI have developed my scientific care
 er at the intersection of biology\, physics and biotechnology. Following t
 he completion of my doctoral thesis on high-risk biological viruses\, I wo
 rked on molecular detection methods\, with a particular focus on the small
 pox virus. I also contributed to the development of an automated genotypin
 g unit for use in forensic science. My research at LIPhy (CNRS) has centre
 d on using phage display to select antibodies and peptides for use in bios
 ensors\, including electronic noses for detecting volatile organic compoun
 ds and pathogens such as Campylobacter jejuni. I have also studied non-can
 onical DNA structures\, such as telomeric G-quadruplexes. My current proje
 cts combine microfluidics\, genomic engineering and modelling to improve o
 ur understanding of bacterial mechanisms\, including strategies for alloca
 ting protein resources and the dynamics of microbial consortia. These proj
 ects have applications in the rapid detection of pathogens\, the developme
 nt of biomolecules that target specific DNA structures and the optimisatio
 n of microbial systems for biotechnological applications. My career path r
 eflects a collaborative and interdisciplinary approach\, combining fundame
 ntal research with applied innovation.\n\n
CATEGORIES:Soutenances
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260528T140000
DTEND;TZID=Europe/Paris:20260528T150000
CREATED:20260331T094511Z
LAST-MODIFIED:20260413T075437Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2070547609
X-TEAMUP-WHO:Natale Scaramozzino
END:VEVENT
BEGIN:VEVENT
UID:TU2057554366
DTSTAMP:20260702T135606Z
SUMMARY:Variational two-scale models in elasticity (Claire Lestringant (Sor
 bonne Université\, Paris))
DESCRIPTION:Who: Claire Lestringant (Sorbonne Université\, Paris)\n\nI wil
 l discuss two classes of effective\, macroscopic models for two-scale syst
 ems in elasticity: (i) 1D models applicable to thin structures\, and (ii) 
 homogenized 2D or 3D continua applicable to materials with a periodic micr
 ostructure. In both systems\, the separation of scales calls for the defin
 ition of macroscopic models that slave fine-scale fluctuations to an effec
 tive\, macroscopic deformation field. I will show how such models can be e
 stablished in a systematic and rigorous way based on a two-scale expansion
  that accounts for both nonlinear and higher-order (i.e. deformation gradi
 ent) effects. I will further demonstrate that the resulting models accurat
 ely predict nonlinear effects\, finite size effects and localization for a
  set of examples. Finally\, I will discuss two challenges that arise when 
 solving these effective models: (1) missed boundary layer effects and (2) 
 negative stiffness associated with higher-order terms.\n\nContact: Emmanue
 l Siéfert\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260601T110000
DTEND;TZID=Europe/Paris:20260601T120000
CREATED:20260310T080937Z
LAST-MODIFIED:20260603T154617Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2057554366
X-TEAMUP-WHO:Claire Lestringant (Sorbonne Université\, Paris)
END:VEVENT
BEGIN:VEVENT
UID:TU2048006478
DTSTAMP:20260702T135606Z
SUMMARY:Applying optogenetics to single cells: do photophysics\, diffusion\
 , compartmentalization\, interactions\, etc.\, really matter? (Antoine Del
 on (IMOV))
DESCRIPTION:Who: Antoine Delon (IMOV)\n\nOptogenetic control of single cell
 s with high spatio-temporal precision is a quite promising technique to be
 tter understand many cellular processes such as motility\, fate or signali
 zation.\n\nWe performed a series of experiments to study membrane recruitm
 ent using either an evanescent single spot photoactivation or a propagativ
 e one. While we initially expected that an evanescent spot would enable a 
 much better spatially localized photoactivation and recruitment\, we obser
 ved mitigated results.\n\nTo understand those results we developed a bioph
 ysical model of our biological system.\n\nTherefore\, we will discuss almo
 st everything you always wanted to know about photophysics\, diffusion\, c
 ompartmentalization and interactions (but were perhaps afraid to ask).\n\n
 Finally\, we will give few cues to improve the spatial resolution of optog
 enetic photoactivation.\n\n
CATEGORIES:Séminaires internes
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260604T110000
DTEND;TZID=Europe/Paris:20260604T120000
CREATED:20260223T091152Z
LAST-MODIFIED:20260603T154511Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2048006478
X-TEAMUP-WHO:Antoine Delon (IMOV)
END:VEVENT
BEGIN:VEVENT
UID:TU2100558946
DTSTAMP:20260702T135606Z
SUMMARY:Soutenance Loïc Lechevallier (Loïc LECHEVALLIER)
DESCRIPTION:Who: Loïc LECHEVALLIER\n\n**Titre : Développement et caracté
 risation d’une source THz à photomélange de lasers IR ultra-stable : a
 pplication à la vapeur d’eau**\n\n
CATEGORIES:Soutenances
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260610T140000
DTEND;TZID=Europe/Paris:20260610T150000
CREATED:20260521T091131Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2100558946
X-TEAMUP-WHO:Loïc LECHEVALLIER
END:VEVENT
BEGIN:VEVENT
UID:TU2094376612
DTSTAMP:20260702T135606Z
SUMMARY:Phase retrieval based on intensity-only spatiotemporal wavefront sh
 aping (Luis Alberto Razo López (Institut Langevin\, Paris))
DESCRIPTION:Who: Luis Alberto Razo López (Institut Langevin\, Paris)\n\nWe
  introduce a phase retrieval framework based solely on intensity measureme
 nts and intensity-only spatiotemporal modulation. Our approach leverages s
 patiotemporal wavefront shaping to encode phase information into temporall
 y multiplexed intensity signals\, which are subsequently decomposed in the
  Fourier domain. We show that the resulting temporal harmonics correspond 
 to spiral-phase–modulated speckle components\, enabling the retrieval of
  phase information without direct phase-sensitive detection. We derive the
  harmonic structure induced by a rotating angular aperture mask and demons
 trate that each harmonic carries a distinct spiral phase and amplitude wei
 ghting governed by a sinc envelope. Based on this structure\, we develop a
 n optimization-based reconstruction algorithm that retrieves both the unkn
 own diffuser phase and system scaling without prior knowledge of the optic
 al transfer function. Experimental results confirm accurate reconstruction
  of diffuser surfaces and aberration correction\, including refocusing thr
 ough digital micromirror device (DMD)-induced distortions.\n\nContact: Dor
 ian Bouchet\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260615T110000
DTEND;TZID=Europe/Paris:20260615T120000
CREATED:20260511T132927Z
LAST-MODIFIED:20260521T134821Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2094376612
X-TEAMUP-WHO:Luis Alberto Razo López (Institut Langevin\, Paris)
END:VEVENT
BEGIN:VEVENT
UID:TU2103371808
DTSTAMP:20260702T135606Z
SUMMARY:[Young Researchers Only]: What do a fish and a diabolo have in comm
 on?​ || Optimising your survival rate in AI-Driven cars.​ (Romane FREY
   - (PhD\, MOVE) || Mathieu LETROU- (Post-Doc\, MC2)​)
DESCRIPTION:Who: Romane FREY  - (PhD\, MOVE) || Mathieu LETROU- (Post-Doc\,
  MC2)​\n\n**What do a fish and a diabolo have in common?​**\n\n*Romane
  FREY- (PhD\, MOVE)*\n\nThe rapid launch of a diabolo into the air when bo
 th ends of its string are suddenly pulled illustrates a simple but effecti
 ve mechanical process. This motion can be interpreted using a simple geome
 tric model in which a folded triangular configuration of a string is quick
 ly straightened under fast traction at its extremities\, transferring mome
 ntum to the central object. The same principle applies to a folded elastic
  membrane. As the ends are pulled apart\, the mass distributed along the m
 embrane is rapidly accelerated\, similarly to how a diabolo is launched. B
 ecause unlike in the diabolo\, the mass is not free\, the sudden transfer 
 of momentum makes the membrane vibrate. The frequency of the sound produce
 d depends on the tension in the membrane. This analogy suggests potential 
 relevance in bioacoustics\, where certain fish species may use similar rap
 id tensioning mechanism to produce loud sounds. In bony fish\, sound produ
 ction relies on the contraction of high-speed muscles that rapidly modulat
 e the tension of a gas-filled organ\, the swim bladder.​\n\n---\n\n**Opt
 imising your survival rate in AI-Driven cars.​**\n\n*Mathieu LETROU - (P
 ost-Doc\, MC2)​*\n\nAs autonomous vehicles become smarter\, an ethical q
 uestion emerges: what happens when your car must decide who lives and who 
 dies? In this talk\, we will explore the scientific research devoted to th
 is problem. Through ethics\, sociology\, economics\, and mathematics point
  of view\, we will examine the different solutions proposed by researchers
  and the challenges they raise for society. By the end\, you will have all
  the tools needed to maximize your chances of survival in a world where dr
 iving licenses have become obsolete. ​\n\n
LOCATION:Conference Room
CATEGORIES:Séminaire des non-permanents
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260626T110000
DTEND;TZID=Europe/Paris:20260626T120000
CREATED:20260526T162445Z
LAST-MODIFIED:20260619T065633Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2103371808
X-TEAMUP-WHO:Romane FREY  - (PhD\, MOVE) || Mathieu LETROU- (Post-Doc\, MC2
 )​
X-TEAMUP-WHERE:Conference Room
ATTACH:https://files.teamup.com/16073145/attachment/01KVFANGMPHWGSMNSZ7S6DD
 D8J/Mathieu_portrait.png?hash=f605af323e155e2f6c347be8a22e126be3e2fdc00604
 39b59b0ef850d67f77a7
ATTACH:https://files.teamup.com/16073145/attachment/01KVFANGN9D7HV1DP0WCA7M
 ZP6/Romane_portrait.JPG?hash=229b1466cff9822b448c6f12d9331fe1ba677bde9b313
 d33217774f0792cdfdc
ATTACH:https://files.teamup.com/16073145/attachment/01KVFANGP3MRGGNGHWTBFKC
 B1P/abstract_fig.png?hash=0edec7fc4bb6beae074122d2ce0ea93ae0e863329f6f3a1c
 cd6e5cbb4965b095
END:VEVENT
BEGIN:VEVENT
UID:TU2113582881
DTSTAMP:20260702T135606Z
SUMMARY:Coupling osmosis and mechanics in vertex-based models for plant tis
 sue growth (Guillaume Mestdagh (INRIA Montbonnot))
DESCRIPTION:Who: Guillaume Mestdagh (INRIA Montbonnot)\n\nUnderstanding pla
 nt growth is fundamental to address global challenges such as food securit
 y\, biodiversity\, and soil‑erosion control. The development of plants i
 nvolves many interconnected physical processes\, occurring at various spat
 ial and temporal scales\, making modeling an indispensable complement to e
 xperiments. In particular\, discrete vertex-based models have successfully
  described the coupling between inter-cell water fluxes and mechanical def
 ormations of cell walls\, in response to a prescribed inner water pressure
 .\n\nA two-dimensional vertex-based model represents a group of cells as a
  tiling of polygons\, with the edges between polygons representing cell wa
 lls. Existing vertex-based models postulate a fixed water pressure inside 
 cells as the force driving growth. In reality\, this inner pressure itself
  is the consequence of osmosis\, a chemical process by which water is attr
 acted into cells with a higher concentration of solute. However\, capturin
 g the interplay between mechanics and solute dynamics in plant tissues int
 o one model remains a challenge that requires novel mathematical framework
 s.\n\nIn this talk\, I will present a new approach to couple solute and wa
 ter fluxes with mechanics and growth in vertex-based models. The proposed 
 approach is based on a variational formalism where the system physics is d
 escribed in terms of free energy and dissipation function. After building 
 the model and deriving the evolution equations of the system\, I will show
  that the resulting formulation can be turned into a numerical method. Fin
 ally\, I will illustrate the model properties through a few numerical simu
 lations and discuss its interest for the study of plant growth.\n\nContact
 : Philippe Marmottant\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260706T110000
DTEND;TZID=Europe/Paris:20260706T120000
CREATED:20260612T135603Z
LAST-MODIFIED:20260622T082129Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2113582881
X-TEAMUP-WHO:Guillaume Mestdagh (INRIA Montbonnot)
END:VEVENT
BEGIN:VEVENT
UID:TU2112803307
DTSTAMP:20260702T135606Z
SUMMARY:PhD defence: Symmetry breaking in biological tissue studied using b
 ioelectricity (Niloofar Pishkari (MicroTiss))
DESCRIPTION:Who: Niloofar Pishkari (MicroTiss)\n\nCell migration is a funda
 mental biological process that enables organisms to respond to environment
 al stimuli and maintain homeostasis.  Disruptions in this process can lea
 d to functional impairment and disease.  Rather than moving randomly\,  
 many cells migrate directionally in response to external cues\, a behavior
  essential for processes such as morphogenesis\, cancer invasion\, and wou
 nd healing.  Understanding the mechanisms underlying directional migratio
 n\, therefore\, requires investigating physiologically relevant guiding st
 imuli.  Among these\, electric fields represent a precise and biologicall
 y significant cue.  In this study\, we used the SCHEEPDOG platform to app
 ly programmable electric fields of varying intensities to keratocytes and 
 quantitatively analyze their migratory behavior.  Our results show that e
 lectric field stimulation induces robust directional migration while incre
 asing migration speed in an intensity-dependent manner.  Cells initially 
 moving randomly progressively align with the field vector\, with higher fi
 eld strengths accelerating this alignment process.  Notably\, although bo
 th migration speed and alignment dynamics are modulated by field intensity
 \,  the overall geometry of migration trajectories remains unchanged. Cel
 ls initially migrating opposite to the field reorient by executing turns w
 hose size and shape are independent of stimulation strength\, indicating t
 hat turning dynamics are preserved.  A key finding of this work is the di
 stinct role of mitochondrial ATP in regulating directional migration. Inhi
 bition of mitochondrial ATP production impaired steering\, reduced directi
 onal responsiveness\, and disrupted alignment dynamics\, particularly unde
 r weak electric fields.  In contrast\, stronger fields partially compensa
 ted for this deficit\, restoring alignment despite reduced speed and slowe
 r response dynamics.  These results indicate that while mitochondrial ATP
  is not strictly required for basal motility\, it is essential for efficie
 nt reorientation and polarity refinement.  Furthermore\, asymmetric mitoc
 hondrial distribution emerges as an important determinant of cell polarity
 \, suggesting that intracellular energy localization contributes to the sp
 atial coordination of directional migration.  Together\, our findings dem
 onstrate that electrical stimulation can independently tune migration spee
 d and directional alignment without altering intrinsic turning behavior\, 
 and highlight the critical role of cellular bioenergetics in migratory con
 trol.  This work provides new insights into how biophysical cues and meta
 bolic states interact to regulate cell migration.\n\n
CATEGORIES:Soutenances
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260709T140000
DTEND;TZID=Europe/Paris:20260709T150000
CREATED:20260611T091737Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2112803307
X-TEAMUP-WHO:Niloofar Pishkari (MicroTiss)
END:VEVENT
BEGIN:VEVENT
UID:TU2123212121
DTSTAMP:20260702T135606Z
SUMMARY:Young Researchers
CATEGORIES:Séminaire des non-permanents
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260724T110000
DTEND;TZID=Europe/Paris:20260724T120000
CREATED:20260629T155721Z
LAST-MODIFIED:20260629T155729Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2123212121
END:VEVENT
BEGIN:VEVENT
UID:TU2125137011
DTSTAMP:20260702T135606Z
SUMMARY:TBA (Claude Inserra (Labtau\, Université Lyon 1))
DESCRIPTION:Who: Claude Inserra (Labtau\, Université Lyon 1)\n\nContact: P
 hilippe Marmottant\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260831T110000
DTEND;TZID=Europe/Paris:20260831T120000
CREATED:20260702T135417Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2125137011
X-TEAMUP-WHO:Claude Inserra (Labtau\, Université Lyon 1)
END:VEVENT
BEGIN:VEVENT
UID:TU1984923542
DTSTAMP:20260702T135606Z
SUMMARY:A biophysicist’s view of a biological oscillator: the circadian c
 lock in cyanobacteria (Irina)
DESCRIPTION:Who: Irina\n\n
CATEGORIES:Séminaires internes
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260910T110000
DTEND;TZID=Europe/Paris:20260910T120000
CREATED:20251106T153136Z
LAST-MODIFIED:20260407T073139Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/1984923542
X-TEAMUP-WHO:Irina
END:VEVENT
BEGIN:VEVENT
UID:TU2110937622
DTSTAMP:20260702T135606Z
SUMMARY:Thermodynamic Wisdom: Decolonising Thermodynamics in the Undergradu
 ate Physics Curriculum (Wilson Poon (University of Edinburgh\, UK))
DESCRIPTION:Who: Wilson Poon (University of Edinburgh\, UK)\n\nAfter descri
 bing the way parts of thermodynamics first arose in the context of colonia
 l and then imperial commerce\, I will go on to argue that bringing student
 s’ attention to this problematic social milieu should be part of the phy
 sics curriculum at university level because the goal of higher education s
 hould go beyond imparting knowledge to engendering wisdom. I then describe
 s how the author has sought to do this by introducing several elements int
 o the author’s course that\, together\, should leave a different ‘afte
 rtaste’ with the students compared to a traditional approach. Perhaps th
 e most interesting result of my effort was to have engendered conversation
 s between students outside of the classroom and the examination hall. I wi
 ll make the case that engendering quality conversations is key to the cult
 ivation of wisdom. The author concludes by briefly surveying related initi
 atives in my department and draws a general lesson from this collective en
 deavour.\n\nContact: Samantha Micciulla\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260917T110000
DTEND;TZID=Europe/Paris:20260917T120000
CREATED:20260608T150257Z
LAST-MODIFIED:20260615T150808Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2110937622
X-TEAMUP-WHO:Wilson Poon (University of Edinburgh\, UK)
END:VEVENT
BEGIN:VEVENT
UID:TU2115011011
DTSTAMP:20260702T135606Z
SUMMARY:Cooking crystalline candies and the ductile to brittle transition i
 n concentrated suspensions
DESCRIPTION:The existence and origin of the ductile to brittle transition i
 n non-Brownian suspensions and pastes is under-explored despite the ubiqui
 ty of such materials in practical applications. We demonstrate the phenome
 non in candies of sugar crystals in a water-protein-fat matrix prepared by
  boiling a sugar-cream-butter mixture (known as `fudge' in some countries)
 . As cooking time or final cooking temperature increases\, we observe a tr
 ansition from a fluid to a ductile solid\, then to a brittle solid that ab
 ruptly fractures in compression. We propose that this is driven by rising 
 solid sugar crystal volume fraction\, and indeed find the same sequence of
  behaviour in a suspension of non-Brownian calcite particles as the solid 
 fraction moves from frictional jamming to random close packing. Particle-b
 ased simulations reveal the sensitivity of the observed phenomenon to boun
 dary conditions.\n\nContact: Samantha Micciulla\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260918T110000
DTEND;TZID=Europe/Paris:20260918T120000
CREATED:20260615T150828Z
LAST-MODIFIED:20260615T150840Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2115011011
END:VEVENT
BEGIN:VEVENT
UID:TU2113445751
DTSTAMP:20260702T135606Z
SUMMARY:TBA (Eva Maria Zunzunegui-Bru (LEPMI\, Grenoble))
DESCRIPTION:Who: Eva Maria Zunzunegui-Bru (LEPMI\, Grenoble)\n\nContact: Si
 mon Gravelle\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20260921T110000
DTEND;TZID=Europe/Paris:20260921T120000
CREATED:20260612T092842Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2113445751
X-TEAMUP-WHO:Eva Maria Zunzunegui-Bru (LEPMI\, Grenoble)
END:VEVENT
BEGIN:VEVENT
UID:TU2072701857
DTSTAMP:20260702T135606Z
SUMMARY:TBA (Joël Marthelot (IUSTI\, Marseille))
DESCRIPTION:Who: Joël Marthelot (IUSTI\, Marseille)\n\nContact: Elsa Bayar
 t\n\n
CATEGORIES:Séminaire labo
CLASS:PUBLIC
TRANSP:OPAQUE
SEQUENCE:0
DTSTART;TZID=Europe/Paris:20261012T110000
DTEND;TZID=Europe/Paris:20261012T120000
CREATED:20260403T170534Z
URL;VALUE=URI:https://teamup.com/kspjx8oo4q8mxg7v8h/events/2072701857
X-TEAMUP-WHO:Joël Marthelot (IUSTI\, Marseille)
END:VEVENT
END:VCALENDAR